Pharmaceutical Use of Cocaine. History of Cocaine Circa 1. As cocaine became a popular ingredient in alcoholic drinks, scientists and pharmaceutical companies were investigating possible medical uses for this drug. German pharmaceutical company Merck began producing very small amounts of the drug in the early 1. Cocaine has a short half life about 60 minutes. But cocaine can stay in your system and be detected in urine 24 days after use. Detection time increases to. When you combine contraband, poverty, desperation and lots of spare time, you get the bizarre world of the smuggler. Everything from cocaine to human beings is. Total output through the late 1. In the US, pharmaceutical company Parke Davis also began producing the drug. Then in the 1. 88. For example, Mercks promotional materials touted the drug as a remedy for the morphine addiction suffered by many former Civil War soldiers. One of the early enthusiasts for the drug was Sigmund Freud who was eager to gain fame and wealth so he could marry. He was interested in the opportunity offered by this new drug and began to experiment on himself and friends. He wrote to his fiancee, I take very small doses of it regularly against depression and against indigestion and with the most brilliant of success. Dr. Freud used this drug on himself and his associates for the next decade and wrote his glowing praise for cocaine in the 7. Uber Cocaine. In 1. Freuds friend Dr. M0GOAet3I4/0.jpg' alt='How Cocaine Is Made Into Crack Cocaine' title='How Cocaine Is Made Into Crack Cocaine' />Koller. The drug not only numbed the eye but restricted bleeding because it tightened up blood vessels. This development was another step forward in the popularity of cocaine in medical use. Production of cocaine began to increase greatly in response to increased medical use. White Wedding by Billy Idol song meaning, lyric interpretation, video and chart position. Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug. It is commonly snorted, inhaled as smoke, or as a solution injected into a vein. Ms Office 2007 Pirated Version on this page. In 1. 88. 3, Merck produced only four tenths of a kilo of the drug. By 1. 88. 5, their production had rocketed to 8. This increase began just two months after Dr. Kollers report on cocaine for eye surgery was published. As further applications valid or not were discovered, the popularity of this drug grew rapidly. Along with pharmaceutical applications, over the counter preparations also began to include cocaine. Patent medications containing cocaine Cocaine toothache drops, Instantaneous CureMetcalfs Coca Wine for fatigue of mind or bodyVoice Tabloids with cocaine, chlorate of potash and borax. Chemists at Parke Davis developed a refinement system that called for partial refinement on site in South America, with the remaining refining taking place at the pharmaceutical company. This discovery made the cocaine industry much more viable, as potency would not be lost while shipping the coca leaves from South America to the US or Europe. In 1. 88. 7, the US Surgeon General recommended that cocaine be used to treat depression, claiming that there was no such thing as cocaine addiction. Cocaines Damage Begins to Show Up. In one incident after another, cocaines addictiveness and physical damage began to show up. Young New York surgeon William Halsted began to investigate its use in surgical procedures. He tested the drug by injecting it into his own arms and legs and the limbs of friends and students, using the hypodermic needle invented in the mid 1. Halsted quickly became a non functional addict and could not practice medicine any longer. Freuds experimentation had its hazards, too. One associate, Ernst von Fleischl Marxzow, had been dealing with a hand injury with large doses of morphine. Dr. Freuds administration of cocaine as a solution for the mans morphine addiction turned him into an addled, morphine cocaine addict who died seven years later. He was the first person known to suffer the paranoia and delusions of bugs crawling under the skin that are common to heavy cocaine addicts. In 1. 89. 5, Freud was still abusing cocaine. While under the influence, he and a colleague performed surgery on Emma Eckstein. The surgery went bad, in part because of the Freuds cocaine abuse. While Emma survived, this nearly fatal error seems to have haunted Freud and led him eventually to give the drug up, despite all its apparent benefits. But by the time Freud gave up the drug, its use had already spread far and wide. It would be another 1. The US Makes the Drug Illegal. In 1. 91. 4, the Harrison Narcotics Act rounded up a list of drugs that had been used in patent medicines or pharmaceutical compounds and put them under federal control. Cocaine was on the list. This change meant that those who were now addicted to cocaine could be arrested if they possessed the drug. Despite reports of some increased use during Prohibition, cocaine was not a newsworthy topic until the second half of the Twentieth Century when cocaine began pouring into the US from South America. Resources See More Cocaine History.